Webinar | From mechanisms to advanced applications of transcranial alternating current stimulation

30 March, 2021 - 30 March, 2021

by Ivan Alekseichuk, PhD

March 30, 2021 16:00 PM GMT+1 / 10:00 AM EST

Neural activity in the brain is inherently complex and includes various forms of coordination on different scales. Transcranial alternating current stimulation (tACS) is a non-invasive method to modulate brain activity using mild oscillating electric fields. Thanks to the control over the frequency and phase of imposed stimulation, tACS is in a great position to manipulate rhythmic neural activity selectively and safely. Here, I will first present the recent animal studies regarding the tACS mechanisms. The conversation will include what we know and what we don't know regarding the neural spike-field coherence, dose-dependency, and frequency specificity of tACS. I will then discuss computational modeling ways to translate animal research to humans. Finally, I will describe two new promising neuromodulatory approaches for targeting neural connectivity - cross-frequency tACS and traveling wave tACS. These methods substantially extend the toolset of available research and therapeutic strategies using non-invasive neuromodulation.

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