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CPM: Conditioned Pain Modulation

Q-Sense Conditioned Pain Modulation (CPM) system for the study of pain mechanisms. Also called « diffuse noxious inhibitory control-like effect » (DNIC)

Q-Sense CPM: a unique device for novel investigations.



The relevance of conditioned pain modulation (CPM), also known as diffuse noxious inhibitory control-like effect (DNIC), has increased in the past few years to become a real topic of interest in the pain research community. As its level of efficiency directly correlates with pain morbidity and vice versa, its potential to predict pain or select the most appropriate drugs for a given condition is very promising. Current investigations rely on the application of a painful pressure at the test site and a conditioning pain best achieved with a container of ice water.

With our Q-Sense CPM system, it becomes possible to study conditioned pain modulation more precisely with an exact control of the temperature at both sites, while electronically recording the whole protocol, including VAS scores, for later processing and analysis.

Some advantages of the Q-Sense CPM system:

  • Software allows tailoring of conditioning protocol
  • Exact control of the noxious stimuli at the test and conditioning sites
  • Electronic record of your results
  • Database platform and report generator
  • Conditioning thermode enabling  fl­exible body site positioning
  • Wide range of tests and methods available (CPM, warm sensation, heat pain and cold sensation thresholds, limits, levels, ramp & hold…)
  • Concomitant pain rating with the computerized visual analog scale (CoVAS)
  • Light-weighted, easily transportable device
  • Intuitive software interface